{"id":1327,"date":"2023-08-26T07:59:40","date_gmt":"2023-08-26T07:59:40","guid":{"rendered":"https:\/\/www.breastaware.gr\/?page_id=1327"},"modified":"2025-08-10T08:20:27","modified_gmt":"2025-08-10T08:20:27","slug":"%ce%b5%ce%be%ce%b5%ce%b9%ce%b4%ce%b9%ce%ba%ce%b5%cf%85%ce%bc%ce%ad%ce%bd%ce%bf%ce%b9-%cf%80%cf%81%ce%bf%cf%83%cf%84%ce%b1%cf%84%ce%b5%cf%85%cf%84%ce%b9%ce%ba%ce%bf%ce%af-%cf%80%ce%b1%cf%81%ce%ac%ce%b3","status":"publish","type":"page","link":"https:\/\/www.breastaware.gr\/en\/%ce%bf-%ce%bc%ce%b1%cf%83%cf%84%cf%8c%cf%82-%ce%bc%ce%bf%cf%85\/%ce%b5%ce%be%ce%b5%ce%b9%ce%b4%ce%b9%ce%ba%ce%b5%cf%85%ce%bc%ce%ad%ce%bd%ce%bf%ce%b9-%cf%80%cf%81%ce%bf%cf%83%cf%84%ce%b1%cf%84%ce%b5%cf%85%cf%84%ce%b9%ce%ba%ce%bf%ce%af-%cf%80%ce%b1%cf%81%ce%ac%ce%b3\/","title":{"rendered":"Specific Protective Factors"},"content":{"rendered":"<div id=\"pl-1327\"  class=\"panel-layout\" ><div id=\"pg-1327-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-1327-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-1327-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><strong>Specialized Preventive Measures for Breast Cancer<\/strong><\/p>\n<p><strong>Protective Factors for High-Risk Women<\/strong><\/p>\n<p>Breast cancer is the most common cancer among women worldwide. Although most cases occur in women without a strong family history, some women belong to <strong>high-risk groups<\/strong> due to genetic mutations (BRCA1, BRCA2), family history, or individual risk factors.<\/p>\n<p>For these cases, there are <strong>specialized preventive interventions<\/strong> with documented efficacy, implemented exclusively after personalized evaluation by a multidisciplinary team (breast surgeon, oncologist, geneticist, psychologist).<\/p>\n<p>&nbsp;<\/p>\n<ol>\n<li><strong>Chemoprevention<\/strong><\/li>\n<\/ol>\n<p>The <strong>Chemoprevention<\/strong> involves the use of preventive pharmacological agents to reduce breast cancer risk in high-risk women.<\/p>\n<p>The most commonly used medications are:<\/p>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;multilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><strong>Tamoxifen<\/strong> (for premenopausal and postmenopausal women)<\/li>\n<\/ul>\n<ul>\n<li aria-setsize=\"-1\" data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;multilevel&quot;}\" data-aria-posinset=\"2\" data-aria-level=\"1\"><strong>Raloxifene<\/strong> (for postmenopausal women)<\/li>\n<\/ul>\n<p>The use of these medications can reduce the risk by 30\u201350%. However, they may cause adverse effects such as hot flashes, increased risk of thromboembolism, or endometrial cancer. The decision should be made in <strong>full medical guidance<\/strong>, weighing the benefits and risks.<\/p>\n<p>&nbsp;<\/p>\n<ol start=\"2\">\n<li><strong>Prophylactic Mastectomy<\/strong><\/li>\n<\/ol>\n<p>The <strong>Prophylactic mastectomy<\/strong> is the surgical removal of both breasts in women with genetic mutations such as BRCA1 or BRCA2.<\/p>\n<p>Surgery can reduce the risk of developing breast cancer by <strong>90\u201395%<\/strong>. Many women choose this measure as a means of prevention and psychological relief. It is often combined with <strong>breast reconstruction<\/strong>, offering improved aesthetic and psychological outcomes.<\/p>\n<p>&nbsp;<\/p>\n<ol start=\"3\">\n<li><strong>Prophylactic Oophorectomy<\/strong><\/li>\n<\/ol>\n<p>The <strong>Prophylactic removal of the ovaries and fallopian tubes<\/strong> (usually laparoscopically) significantly decreases estrogen production, which is implicated in hormone-dependent breast cancer development.<\/p>\n<p>It is indicated for women with BRCA mutations, primarily after completion of childbearing.<br \/>\nThe surgery reduces both the <strong>risk of breast cance<\/strong> as well as the <strong>risk of ovarian cancer<\/strong>. At the same time, it is associated with <strong>early menopause<\/strong> and effects such as hot flashes, mood disturbances, reduced bone density, and decreased fertility \u2014 therefore requiring <strong>multidisciplinary support.<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Personalized Prevention: A Powerful Tool<\/strong><\/p>\n<p>None of the above measures is appropriate for every woman. The <strong>individualized prevention<\/strong> is based on comprehensive medical assessment and respect for the woman\u2019s personal choices and values.<\/p>\n<p>If you belong to a high-risk group, <strong>do not face it alone<\/strong>. Seek support from a specialized multidisciplinary team and learn about options that could <strong>save your life.<\/strong>.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Learn More at breastaware.gr<\/strong><\/p>\n<p>The <i>breastaware.gr<\/i> is a reliable and contemporary online resource providing information on <strong>breast cancer<\/strong>, prevention, and care. With evidence-based content from experts, it empowers every woman to make informed health decisions.<\/p>\n<p><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Bibliography:<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:true,&quot;134233118&quot;:true,&quot;201341983&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">1.Cuzick J, Sestak I, Bonanni B, et al. Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data. <\/span><i><span data-contrast=\"auto\">Lancet<\/span><\/i><span data-contrast=\"auto\">. 2013;381(9880):1827\u20131834.<\/span><br \/>\n<span data-contrast=\"auto\">2.<\/span> <span data-contrast=\"auto\">Rebbeck TR, Kauff ND, Domchek SM. Meta-analysis of risk reduction estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriers. <\/span><i><span data-contrast=\"auto\">J Natl Cancer Inst<\/span><\/i><span data-contrast=\"auto\">. 2009;101(2):80\u201387.<\/span><br \/>\n<span data-contrast=\"auto\">3. Domchek SM, Friebel TM, Singer CF, et al. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. <\/span><i><span data-contrast=\"auto\">JAMA<\/span><\/i><span data-contrast=\"auto\">. 2010;304(9):967\u2013975.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:true,&quot;134233118&quot;:true,&quot;201341983&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-1327-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-1327-0-1-0\" class=\"so-panel widget widget_pw_person_profile widget-person-profile panel-first-child\" data-index=\"1\" >\n\t<div class=\"person-profile  h-card\">\n\t\t\t\t\t\t<div class=\"person-profile__container\">\n\t\t\t<div class=\"person-profile__basic-info\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"person-profile__name  p-name\">\n\t\t\t\t\t\t\t\t\t\tApostolos Mitrousias, MD, MSc\t\t\t\t\t\t\t\t\t\t<\/h4>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"person-profile__label\">\n\t\t\t\t\t\tBreast Surgeon \u2013 Specialist in Breast Diseases, Military Medical Officer\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"person-profile__specific-location\">\n\t\t\t\t\t43 Lazaraki St., Glyfada 16675, Athens, Greece\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"person-profile__icon-list  icon-list\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__item  icon-list__item--featured\">\n\t\t\t\t\t\t\t<i class=\"fa  fa-phone\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__content\">\n\t\t\t\t\t\t\t\t<div class=\"icon-list__description\">\n\t\t\t\t\t\t\t\t\tTelephone\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__text\">\n\t\t\t\t\t\t\t\t\t2108945553\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__item  icon-list__item--default\">\n\t\t\t\t\t\t\t<i class=\"fa  fa-envelope-o\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__text\">\n\t\t\t\t\t\t\t\t\tinfo@breastaware.gr\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__item  icon-list__item--default\">\n\t\t\t\t\t\t\t<i class=\"fa  fa-angle-right\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__text\">\n\t\t\t\t\t\t\t\t\tSince 2017\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__item  icon-list__item--default\">\n\t\t\t\t\t\t\t<i class=\"fa  fa-angle-right\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__text\">\n\t\t\t\t\t\t\t\t\tIntegrated surgical, oncological, and post-surgical management\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__item  icon-list__item--default\">\n\t\t\t\t\t\t\t<i class=\"fa  fa-angle-right\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon-list__text\">\n\t\t\t\t\t\t\t\t\tBreast Care Department \u2013 Secretary: Mirsini Tzamtzi\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t<a class=\"btn  btn-secondary  btn-block  person-profile__button\" href=\"mailto:info@breastaware.gr\" target=\"_blank\">Contact us<\/a>\n\t\t\t\n\t\t<\/div>\n\t<\/div>\n\n<\/div><div id=\"panel-1327-0-1-1\" class=\"so-panel widget widget_pw_opening_time widget-opening-time panel-last-child\" data-index=\"2\" ><div class=\"panel-widget-style panel-widget-style-for-1327-0-1-1\" >\t\t\t<div class=\"opening-time\">\n\t\t\t\t\t\t\t<div class=\"opening-time__item\">\n\t\t\t\t\t<div class=\"opening-time__day\">\n\t\t\t\t\t\tDaily\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"opening-time__time\">\n\t\t\t\t\t\t10:00-14:00 &amp; 17:00-21:00\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"opening-time__item\">\n\t\t\t\t\t<div class=\"opening-time__day\">\n\t\t\t\t\t\tSaturday\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"opening-time__time\">\n\t\t\t\t\t\t10:00 - 14:00\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u0395\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u039c\u03ad\u03c4\u03c1\u03b1 \u03a0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u039a\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c4\u03bf\u03c5 \u039c\u03b1\u03c3\u03c4\u03bf\u03cd \u03a0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03af \u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u0393\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03a5\u03c8\u03b7\u03bb\u03bf\u03cd \u039a\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u039f \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b1\u03c3\u03c4\u03bf\u03cd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2. \u0391\u03bd \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03cc \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03ba\u03ac\u03c0\u03bf\u03b9\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03ae\u03ba\u03bf\u03c5\u03bd \u03c3\u03b5 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03bb\u03cc\u03b3\u03c9 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ce\u03bd \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03c9\u03bd (BRCA1, BRCA2), \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03bf\u03cd \u03ae \u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd. \u0393\u03b9\u03b1 &hellip;<\/p>","protected":false},"author":1,"featured_media":1638,"parent":1409,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":{"0":"post-1327","1":"page","2":"type-page","3":"status-publish","4":"has-post-thumbnail","6":"clearfix","7":"article"},"acf":[],"_links":{"self":[{"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/pages\/1327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/comments?post=1327"}],"version-history":[{"count":0,"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/pages\/1327\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/pages\/1409"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/media\/1638"}],"wp:attachment":[{"href":"https:\/\/www.breastaware.gr\/en\/wp-json\/wp\/v2\/media?parent=1327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}